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About New Member Registration
In order to control spam, we use a two step process. First, use the "Register" feature to create your account. You won't be able to post, yet. The second step is to email "parkins1@parkinsonsonline.org" and let us know that you want upgraded to full status.
Registered Users: To catch up on what has happened while you were away:
1 - Use "View New Posts" above to view material added since you were last here.
2 - Use "View Active Topics" to look in on current discussions.
3 - Use the link below to jump to the blog.
There! You are caught up! - 1 Topics
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Last post by parkins1
Wed Jun 03, 2009 9:30 pm
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About New Member Registration
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A Matter of Balance - A Blog
http://parkinsonsonline.org/blog1/
There are two venues for discussion. One is Caduceus just below this and is intended to be for general Community discussion and support. The other venue is the blog linked above. It is intended to be a somewhat structured environment of a "techie" nature. Please feel free to use both. - 1 Topics
- 1 Posts
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Last post by parkins1
Thu Jul 23, 2009 7:05 am
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Caduceus - Part Pub, Part Cafe - A place to talk.
The Caduceus of Mercury has been linked to medicine for over twelve centuries. Two serpents entwined about one staff invokes the Eastern idea of duality. While many interpretations can come from this, here it is the interaction of two minds yielding knowledge. There lies our goal. - 6 Topics
- 12 Posts
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Last post by carolm
Wed May 20, 2009 4:27 pm
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The Parkinson's - Stress Project
We know that stress has a big role in PD that is only now being looked at. If you are a PWP, it is likely that you are hypersensitive to stress and that stressors such as confrontation dramatically increase your symptoms. It is also likely that, compared to the general population, you have had a much higher level of stress in your life. We feel these to be important clues and work to make sense of them here.
Subforums: -----The Results of a Survey of PWP---------------------------------------------, -----Stress, PD, and the Endocrine System-------------------------------------- - 11 Topics
- 11 Posts
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Last post by parkins1
Fri Nov 13, 2009 8:12 am
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A Summation
For those in a hurry we begin at the end.
"When, however, the nature of the subject, and the circumstances under which it has been here taken up, are considered, it is hoped that the offering of the following pages to the attention of the medical public, will not be severely censured. The disease, respecting which the present inquiry is made, is of a nature highly afflictive. Notwithstanding which, it has not yet obtained a place in the classification of nosologists; some have regarded its characteristic symptoms as distinct and different diseases, and others have given its name to diseases differing essentially from it; whilst the unhappy sufferer has considered it as an evil, from the domination of which he had no prospect of escape." (James Parkinson, London, 1817) - 2 Topics
- 12 Posts
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Last post by parkins1
Sun May 24, 2009 3:16 pm
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A New Look at Parkinson's
The search for a single cause will fail if there are multiple causes. After 200 years it is time we realized that a new look is needed and that far more than a tiny area of the brain and a single neurotransmitter are involved.
Subforums: 1.00 The Problem With Parkinson's Disease -----------------------------------------------, ---------1.0 Discussion---------------, 2.00 The Reality of Parkinson's Disease---------------------------------------, -----2.01 Symptoms--------------------------------------, ----------2.01.01 Blood Pressure --------------------------, -----2.02 Side Effects of Medications-----------------------------------------, ----------2.02.01 Dyskinesias------------------------------, ----------2.02.02 Mitochondrial Inhibition---------------------------, -----2.03 PD Through History----------------------------------------, -----2.04 Newly Diagnosed?--------------------------------------------, ----------2.0 Discussion------------, 3.00 So, What is PD? The Chinese Restaurant Model------------------------, -----3.01 Multiple factors from the Beginning-----------------------------, -----3.02 Ongoing Processes Throughout Life-------------------------------, ----------3.02.01 Inflammation and LPS---------------------------, ----------3.02.02 Oxidation--------------------------------, ----------3.02.03 Mitochondrial failure-----------------------------, ----------3.02.04 Chronic Stress Response---------------------------, ----------3.02.05 Autoimmunity----------------------------, ----------3.02.06 Misfolded Proteins-----------------------------, ----------3.02.07 Excitotoxicity------------------------------, ----------3.02.08 Microglial Activation-------------------------------, ----------3.02.09 Endothelial Failure--------------------------------, -----3.03 System Collapse at the End------------------------------, ----------3.03.01 Autonomic Failure----------------------------, ----------3.03.02 Adrenal Collapse------------------------------, ----------3.0 Discussion---------- - 37 Topics
- 60 Posts
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Last post by parkins1
Sun Jul 26, 2009 8:45 pm
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A Cascade of Causes and Contributions
A sprawling collection of factors which may cause or influence the course of Parkinson's Disease. Not one cause but many laid upon a common foundation is a more realistic explanation of the reality we observe.
Subforums: 4.01 Prenatal Environment and Parkinson's Disease-------------------------------, -----4.01.01 Prenatal LPS--------------------------------------, -----4.01.02 Prenatal Stress--------------------------------------, -----4.01.03 Prenatal Programming and the Adult--------------------------------------, ----------4.01 Discussion---------------------, 4.02 Chronic Exposure to Bacterial Endotoxin LPS and Parkinson's Disease---------, -----4.02.01 Individual Sensitivity-----------------------------------------, -----4.02.02 LPS and the CNS-------------------------------------, -----4.02.03 LPS and the Immune System-------------------------------------------, -----4.02.04 LPS and the Endocrine System--------------------------------------, -----4.02.05 LPS and the GI System----------------------------------------, -----4.02.06 LPS and PD Linkages---------------------------------------, -----4.02.07 LPS Sources--------------------------------------, -----4.02.08 LPS Detoxification----------------------------------------, ----------4.02 Discussion----------, 4.03 Endocrine System, Stress, and Parkinson's Disease---------, -----4.03.01 The Endocrine System and the HPAA--------, -----4.03.02 The HPAA and Parkinson's Disease, -----4.03.03 Stress and Parkinson's Disease, -----4.03.04 Stress and the Nervous System, -----4.03.05 Stress and the Immune System, -----4.03.06 Stress and the GI system, -----4.03.07 Variations in stress sensitivity, ----------4.03 Discussion----------------, 4.04 Chronic Neuroinflammation and Parkinson's Disease-----------------------------, ----------4.04 Discussion--------------------------------, 4.05 Inflammation, Endothelial Failure, and Parkinson's Disease---------------------, -----4.05.01 Inflammation---------------------------------, -----4.05.02 Endothelial Failure and Leaky Gut-----------------------------, -----4.05.03 Endothelial Failure and the Blood Brain Barrier-----------------------------, ----------4.05 Discussion-----------------------------, 4.06 Disruption of Rhythm and Sleep in Parkinson's Disease------------------, -----4.06.01 Time keeping rhythms and PD-------------------------------------, -----4.06.02 Circadian Rhythms and PD--------------------------, -----4.06.03 Sleep and PD-----------------------------, 4.07 Cytokines, Hormones, Neurotransmitters, and Disruption of Neurofunction-----, -----4.07.01 Neuroactive Chemistry and Parkinson's Disease----------------, -----4.07.02 Cytokines-------------------------, -----4.07.03 Hormones---------------------------, ----------4.07.03.01 Cortisol and CRH--------------------------------------, -----4.07.04 Neurotransmitters------------------------, ----------4.07.04.01 Dopamine Synthesis Problems--------------------, ----------4.07.04.02 Dopamine Destruction---------------------------, ----------4.07.04.05 Noradrenaline--------------------------, ----------4.07.04.10 Serotonin------------------------------, ----------4.07 Discussion-----------------------------, 4.08 Metabolic and Nutritional Factors in Parkinson's Disease-------------------------, -----4.08.01 Diabetes, Glycemia, and Parkinson's Disease-------------------------------, -----4.08.02 Metabolic Syndromes and Parkinson's Disease, -----4.08.03 Nutrient Malabsoption, Transport, Enzymes, Co-factors, -----4.08.04 Food Intolerance, Lectins, and Cross Reactivity, -----4.08.05 Vitamin D3 -----------------------------, -------------------------4.08 Discussion-------------------------, 4.09 Neuropeptide Dysfunction------------------------------, 4.10 Genetics and Epigenetics---------------------------------, 4.11 Hypoxia------------------------------------------------------------, 4.12 Cellular Disorders--------------------------------------------------------------------------, -----4.12.01 Mitochondrial Dysfunction-----------------------------, 4.13 Pathogens---------------------------------------------------, 4.14 Related Disorders---------------------------------------------------------------, -----4.14.10 Normal Pressure Hydrocephalus---------------------------------------, -----4.14.11 Post Traumatic Stress Disorder---------------------------, 4.15 Gastrointestinal Factors-----------------------------------------------------, ---------------4.15 Discussion-----------------, 4.16 Electrolytes and PD---------------------------------------------------, 4.17 Vagus Nerve----------------------------------------------------, 4.18 Neuromelanin, Alpha Synuclein, Misfolded Proteins, and Lewy Bodies----, 4.19 Pollutants and Environmental Toxins----------------------------, 4.20 Vaccines, Dental Amalgams, and Other Controversies--------------- - 188 Topics
- 339 Posts
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Last post by parkins1
Thu Aug 20, 2009 8:01 am
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Systems and Synergy
A broader view of neurodegenerative illness as a system wide process over riding the artificial boundaries we have erected for our own convenience but which Nature ignores.
Subforums: 10.01 Synergy and Amplification of Effect-------------------, 10.02 Immune System and PD--------------------------, -----10.021 PD, Lipopolysaccharide (LPS), and Microglia in the SN--------------------------, ----------10.02 Discussion--------------------------------, -----10.020 Overview Immune PD Interacton-----------------, 10.03 Endocrine System and PD-------------------, -----10.030 Endocrine - PD Overview--------------------------------, -----10.031 PD, Cushing's Syndrome, and System Collapse----------------------------, -----10.032 PD, Glycemic Control, and Hyperglycemia------------------------------, ----------10.03 Discussion----------------------------, 10.04 GI System and PD--------------------, -----10.041 PD, Constipation, and Leaky Gut----------------------------, ----------10.04 Discussion---------------------------, 10.05 Nervous System and PD-----------------, -----10.051 PD and Neuroactive Chemistry---------------------------, ----------10.05 Discussion-----------------------------, 10.06 System Interactions - PD as a Whole, -----10.06.01 Immune and CNS interactions------------------------------, -----10.06.02 Immune (LPS) and Endocrine (HPA)----------------------, ----------Discussion--------- - 10 Topics
- 13 Posts
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Last post by parkins1
Sun Jul 12, 2009 7:21 am
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Therapeutic Possibilities
Subforums: About this section - must read!---------------------------------------, 20.1 Botanical Therapies------------------------------, -----20.11 Turmeric / Curcumin-(Protective, Adaptogen)--------------------------------, -----20.12 Ginkgo biloba--(Protective, adaptogen, mitochondria)----------------------------, -----20.13 Ashwagandha--(Restorative, functional)---------------------------, -----20.14 Astragalus--(Restorative)-------------------------------, -----20.15 Ginseng---(Restorative, protective, adaptogen)-------------------------, -----20.16 Royal jelly--(Restorative, protective)-----------------------------, -----20.17 Green tea / Theanine-------------------------, -----20.18 Silymarin---(Protective) -------------------------, -----20.19 Triptolide (Protective)---------------------------, -----20.20 Baicalein--(Restorative, Protective)----------------------------, -----20.21 Mucuna pruriens------------------------------, -----20.22 Spikenard--(Restorative)----------------------------, -----20.23 Rhodiola--------------------------------, -----20.24 Bilberry--(Protective, mitochondria)----------------------------, -----20.25 Resveratrol------------------------------, -----20.26 Boswellia-----------------------------, -----20.27 St. John's Wort------------------------------, -----20.28 Kava kava-----------------------------, -----20.29 Valerian--------------------------------, -----20.30 Bacopa monniera----------------------------, -----20.31 Convolvulus pluricaulis---------------------------, -----20.32 Ginger----------------------------------, ------20.33 General Polyphenols------------------------------, ----------20.1 Discussion-------------------------, 22.1 Dietary supplements--------------------------------, -----22.11 L-Arginine-----------------------------------------------------------, -----22.12 Methionine-------------------------------, -----22.13 Vitamin D3-----------------------------, -----22.14 Folic Acid---------------------------------, -----22.15 Creatine-----------------------------, -----22.16 Acetyl-L-Carnitine/Alpha-Lipoic-Acid-------------------------, -----22.17 CDP-Choline------------------------------, 25.1 Mitigation Therapies----------------------------, -----25.11 Antioxidants---------------------------------, -----25.21 Anti-inflammatories--------------------------------, -----25.31 Anti-stress-------------------------------, 30.1 Metabolic Therapies and Parkinson's------------------------------, ----------30.1 Discussion------------------------------, 40.1 Orphanned Therapies-------------------, ------40.11 Vibrational therapy-----------------------------, -----40.12 Light Therapy--------------------------------, -----40.13 Methylene Blue---------------------------, ----------40.1 Discussion-------------------------, 50.1 Hormonal Therapies-------------------------, ----------50.1 Discussion----------------------, 60.1 Peptide Therapies-----------------------------, -----60.11 GLP-1, CRF-1, Ex-4-----------------------------, -----60.12 GLP-1 Therapy---------------------------, -----60.13 CRF-1 Therapy---------------------------, -----60.14 Nerve Growth Factors Therapy----------------------------, ----------60.1 Discussion---------------------------, 70.1 Dietary Therapies-----------------------------, -----70.11 Fats and fatty acids--------------------------------------------, -----70.12 Dopamine Precursors----------------------------------------, -----70.13 Caloric Restriction----------------------------------, -----70.14 Micronutrients---------------------------------, ----------70.1 Discussion------------------------------, 80.1 Electrical stimulation-----------------------------, ----------80.1 Discussion------------------------------, 90.1 Ayurveda and TCM------------------------------, ----------90.1 Discussion-------------------------------- - 116 Topics
- 186 Posts
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Last post by parkins1
Thu Jul 23, 2009 5:43 am
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Administration
FAQ - Contact - About - etc
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Patient's Voices
What patients want the rest of the PD community to know
Subforums: To Doctors-----------------------------------------------, To Researchers--------------------------------------, -----------Discussion----------, The White Rats----------------------------- - 4 Topics
- 6 Posts
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Last post by joopoele
Sun Mar 15, 2009 6:36 am
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